Publications - Workgroup For The Liver

Go to content

Main menu:


Update: 2020/10/15


Berndt N, Eckstein J, Heucke N, Wuensch T, Gajowski R, Stockmann M, Meierhofer D, Holzhütter HG.
Metabolic Heterogeneity of Human Hepatocellular Carcinoma (HCC): Implications for Personalized Pharmacological Treatment.

FEBS J. 2020. Online ahead of print.


Dziodzio T, Öllinger R, Schöning W, Rothkäppel A, Nikolov R, Juraszek A, Ritschl PV, Stockmann M, Pratschke J, Jara M.
Validation of a new prognostic model to predict short and medium-term survival in patients with liver cirrhosis.

BMC Gastroenterol. 2020;20:265.


Alraish R, Wicha SG, Frey OR, Roehr AC, Pratschke J, Stockmann M, Wuensch T, Kaffarnik M.
Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx).

Ann Intensive Care. 2020;10:106.


Bednarsch J, Blüthner E, Karber M, Gerlach UA, Pascher A, Maasberg S, Pevny S, Pratschke J, Pape UF, Stockmann M.
Oral intake and plasma citrulline predict quality of life in patients with intestinal failure.

Nutrition. 2020;79-80:110855.


Blüthner E, Jara M, Shrestha R, Faber W, Pratschke J, Stockmann M, Malinowski M.
Future liver remnant function as a predictor of postoperative morbidity following liver resection for hepatocellular carcinoma - A risk factor analysis.

Surg Oncol. 2020;33:257-265.


Wizenty J, Schumann T, Theil D, Stockmann M, Pratschke J, Tacke F, Aigner F, Wuensch T.
Recent Advances and the Potential for Clinical Use of Autofluorescence Detection of Extra-Ophthalmic Tissues.

Molecules 2020, 25, 2095.


Blüthner E, Pape UF, Stockmann M, Karber M, Maasberg S, Pevny S, Gerlach-Runge U, Pascher A, Pratschke J, Tacke F, Bednarsch J.
Assessing Non-Invasive Liver Function in Patients with Intestinal Failure Receiving Total Parenteral Nutrition-Results from the Prospective PNLiver Trial.

Nutrients. 2020;12:E1217.


Nee J, Schroeder T, Vornholt F, Schaeuble J, Leithner C, Stockmann M, Storm C.
Dynamic determination of functional liver capacity with the LiMAx test in post-cardiac arrest patients undergoing targeted temperature management-A prospective trial.

Acta Anaesthesiol Scand. 2020;64:501-507.


Holzhütter HG, Wuensch T, Gajowski R, Berndt N, Bulik S, Meierhofer D, Stockmann M.
A novel variant of the  13C-methacetin liver function breath test that eliminates the confounding effect of individual differences in systemic CO2 kinetics.

Arch Toxicol. 2020;94:401-415.


Nee J, Schroeder T, Vornholt F, Schaeuble J, Leithner C, Stockmann M, Storm C.
Dynamic determination of functional liver capacity with the LiMAx Test in post-cardiac arrest patients undergoing Targeted Temperature Management - a prospective trial.

Acta Anaesthesiol Scand. 2020;64:501-507.


Blüthner E, Bednarsch J, Malinowski M, Binder P, Pratschke J, Stockmann M, Kaffarnik M.
Dynamic liver function is an independent predictor of recurrence-free survival after curative liver resection for HCC - A retrospective cohort study.

Int J Surg. 2019;71:56-65.


Theilig D, Tsereteli A, Elkilany A, Raabe P, Lüdemann L, Malinowski M, Stockmann M, Pratschke J, Hamm B, Denecke T, Geisel D.
Gd-EOB-DTPA-enhanced MRI T1 relaxometry as an imaging-based liver function test compared with 13C-methacetin breath test.

Acta Radiol. 2020;61:291-301.


Berndt N, Eckstein J, Heucke N, Gajowski R, Stockmann M, Meierhofer D, Holzhütter HG.
Characterization of Lipid and Lipid Droplet Metabolism in Human HCC.

Cells. 2019;8.


Rohwer N, Jumpertz S, Erdem M, Egners A, Warzecha KT, Fragoulis A, Kühl AA, Kramann R, Neuss S, Rudolph I, Endermann T, Zasada C, Apostolova I, Gerling M, Kempa S, Hughes R, Lewis CE, Brenner W, Malinowski MB, Stockmann M, Schomburg L, Faller W, Sansom OJ, Tacke F, Morkel M, Cramer T.
Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.

Oncogene. 2019;38:5670-5685.


Wuensch T, Wizenty J, Quint J, Spitz W, Bosma M, Becker O, Adler A, Veltzke-Schlieker W, Stockmann M, Weiss S, Biebl M, Pratschke J, Aigner F.
Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer.

Gastroenterol Res Pract.


Theilig D, Steffen I, Malinowski M, Stockmann M, Seehofer D, Pratschke J, Hamm B, Denecke T, Geisel D.
Predicting liver failure after extended right hepatectomy following right portal vein embolization with gadoxetic acid-enhanced MRI.

Eur Radiol. 2019;29:5861-5872.


Wuensch T, Heucke N, Wizenty J, Quint J, Sinn B, Arsenic R, Jara M, Kaffarnik M, Pratschke J, Stockmann M.
Hepatic CYP1A2 activity in liver tumors and the implications for preoperative volume-function analysis.

Am J Physiol Gastrointest Liver Physiol. 2019;316:G608-G614.


Blüthner E, Bednarsch J, Pape UF, Karber M, Maasberg S, Gerlach UA, Pascher A, Wiedenmann B, Pratschke J, Stockmann M.
Advanced liver function assessment in patients with intestinal failure on long-term parenteral nutrition.

Clin Nutr. 2019.


Blüthner E, Bednarsch J, Stockmann M, Karber M, Pevny S, Maasberg S, Gerlach UA, Pascher A, Wiedenmann B, Pratschke J, Pape UF.
Determinants of Quality of Life in Patients With Intestinal Failure Receiving Long-Term Parenteral Nutrition Using the SF-36 Questionnaire: A German Single-Center Prospective Observational Study.

JPEN J Parenter Enteral Nutr. 2019.
In print.


Heucke N, Wuensch T, Mohr J, Kaffarnik M, Arsenic R, Sinn B, Müller T, Pratschke J, Stockmann M, Sack I, Tzschätzsch H.
Non-invasive structure-function assessment of the liver by 2D time-harmonic elastography and the dynamic Liver MAximum capacity (LiMAx) test.

J Gastroenterol Hepatol. 2019.
In print.


Wuensch T, Quint J, Mueller V, Mueller A, Wizenty J, Kaffarnik M, Kern B, Stockmann M, Biebl M, Pratschke J, Aigner F.
Identification of serological markers for pre- and postoperative fasting periods.

Clin Nutr ESPEN. 2019; 30:131-137.


Blüthner E, Jara M, Shrestha R, Faber W, Pratschke J, Stockmann M, Malinowski M.
The predictive value of future liver remnant function after liver resection for HCC in noncirrhotic and cirrhotic patients.

HPB (Oxford) . 2019;21:912-922.


Jara M, Dziodzio T, Malinowski M, Lüttgert K, Nikolov R, Ritschl PV, Öllinger R, Pratschke J, Stockmann M.
Prospective Assessment of Liver Function by an Enzymatic Liver Function Test to Estimate Short-Term Survival in Patients with Liver Cirrhosis.

Dig Dis Sci. 2019;64:576-584.


Stockmann M, Vondran FWR, Fahrner R, Tautenhahn HM, Mittler J, Bektas H, Malinowski M, Jara M, Klein I, Lock JF; Collaborative Fast‐track Liver Study Group.
Randomized clinical trial comparing liver resection with and without perioperative assessment of liver function.

BJS Open. 2018;2:301-309.


Berndt N, Bulik S, Wallach I, Wünsch T, König M, Stockmann M, Meierhofer D, Holzhütter HG.
HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology.

Nat Commun. 2018;9:2386.


Wizenty J, Ashraf MI, Rohwer N, Stockmann M, Weiss S, Biebl M, Pratschke J, Aigner F, Wuensch T.
Autofluorescence: A potential pitfall in immunofluorescence-based inflammation grading.

J Immunol Methods. 2018;456:28-37.


Major RD, Kluge M, Jara M, Nösser M, Horner R, Gassner J, Struecker B, Tang P, Lippert S, Reutzel-Selke A, Geisel D, Denecke T, Stockmann M, Pratschke J, Sauer IM, Raschzok N.
The Predictive Value of the Maximal Liver Function Capacity Test for the Isolation of Primary Human Hepatocytes.

Tissue Eng Part C Methods. 2018;24:179-186.


Hillebrandt KH, Arsenic R, Hofmann J, Eurich D, Gül S, Strücker B, Sauer IM, Pratschke J, Stockmann M, Raschzok N.
Acute Graft Dysfunction 17 Years After Liver Transplant: A Challenging Clinical and Histologic Manifestation of Hepatitis E.

Exp Clin Transplant. 2018;16:348-351.


Heidenreich S, Witte N, Weber P, Goehring I, Tolkachov A, von Loeffelholz C, Döcke S, Bauer M, Stockmann M, Pfeiffer AFH, Birkenfeld AL, Pietzke M, Kempa S, Muenzner M, Schupp M.
Retinol saturase coordinates liver metabolism by regulating ChREBP activity.

Nat Commun. 2017;8:384.


Stockmann M, Bednarsch J, Malinowski M, Blüthner E, Pratschke J, Seehofer D, Jara M.
Functional considerations in ALPPS - consequences for clinical management.

HPB (Oxford). 2017;19:1016-1025.


Kaffarnik M, Stoeger G, Liebich J, Grieser C, Pratschke J, Stockmann M.
Liver Function, Quantified by LiMAx Test, After Major Abdominal Surgery. Comparison Between Open and Laparoscopic Approach.

World J Surg. 2018;42:557-566.


Rubin TM, Heyne K, Luchterhand A, Jan Bednarsch, W R Vondran F, Polychronidis G, Malinowski M, Nikolic A, Tautenhahn HM, Jara M, Wünsch T, Stockmann M, Friso Lock J.
Kinetic validation of the LiMAx test during 10 000 intravenous  13C-methacetin breath tests.

J Breath Res. 2017;12:016005.


Wicha SG, Frey OR, Roehr AC, Pratschke J, Stockmann M, Alraish R, Wuensch T, Kaffarnik M.
Linezolid in liver failure: exploring the value of the maximal liver function capacity (LiMAx) test in a pharmacokinetic pilot study.

Int J Antimicrob Agents. 2017;50:557-563.


Kaffarnik MF, Ahmadi N, Lock JF, Wuensch T, Pratschke J, Stockmann M, Malinowski M.
Correlation between plasma endothelin-1 levels and severity of septic liver failure quantified by maximal liver function capacity (LiMAx test). A prospective study.

PLoS One. 2017;12:e0178237.


Lock JF, Westphal T, Rubin T, Malinowski M, Schulz A, Jara M, Bednarsch J, Stockmann M.
LiMAx Test Improves Diagnosis of Chemotherapy-Associated Liver Injury Before Resection of Colorectal Liver Metastases.

Ann Surg Oncol. 2017;24:2447-2455.


Schütz E, Fischer A, Beck J, Harden M, Koch M, Wuensch T, Stockmann M, Nashan B, Kollmar O, Matthaei J, Kanzow P, Walson PD, Brockmöller J, Oellerich M.
Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study.

PLoS Med. 2017;14:e1002286.


von Loeffelholz C, Pfeiffer AFH, Lock JF, Lieske S, Döcke S, Murahovschi V, Kriebel J, de Las Heras Gala T, Grallert H, Rudovich N, Stockmann M, Spranger J, Jahreis G, Bornstein SR, Lau G, Xu A, Schulz-Menger J, Exner L, Haufe S, Jordan J, Engeli S, Birkenfeld AL.
ANGPTL8 (Betatrophin) is Expressed in Visceral Adipose Tissue and Relates to Human Hepatic Steatosis in Two Independent Clinical Collectives.

Horm Metab Res. 2017;49:343-349.


Wuensch T, Ruether DF, Zöllner C, Mueller T, Jung T, Kaffarnik M, Kassner U, Schott E, Kiefer S, Pratschke J, Stockmann M, Jara M.
Performance characterization of a novel electronic number connection test to detect minimal hepatic encephalopathy in cirrhotic patients.

Eur J Gastroenterol Hepatol. 2017;29:456-463.


Geisel D, Raabe P, Lüdemann L, Malinowski M, Stockmann M, Seehofer D, Pratschke J, Hamm B, Denecke T.
Gd-EOB-DTPA-enhanced MRI for monitoring future liver remnant function after portal vein embolization and extended hemihepatectomy: A prospective trial.

Eur Radiol. 2017;27:3080-3087.


Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B Jr, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A.
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.

Gut. 2017;66:473-486.


Raschzok N, Schott E, Reutzel-Selke A, Damrah I, Gül-Klein S, Strücker B, Sauer IM, Pratschke J, Eurich D, Stockmann M.
The impact of directly acting antivirals on the enzymatic liver function of liver transplant recipients with recurrent hepatitis C.

Transpl Infect Dis. 2016;18:896-903.


von Loeffelholz C, Döcke S, Lock JF, Lieske S, Horn P, Kriebel J, Wahl S, Singmann P, de Las Heras Gala T, Grallert H, Raschzok N, Sauer IM, Heller R, Jahreis G, Claus RA, Bauer M, Stockmann M, Birkenfeld AL, Pfeiffer AFH.
Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver.

Hepatol Res. 2017;47:890-901.


Rubin T, von Haimberger T, Helmke A, Lock JF, Stockmann M, Heyne K.
Liver Status Assessment by Spectrally and Time Resolved IR Detection of Drug Induced Breath Gas Changes.

Photonics 2016, 3, 31.


Bednarsch J, Blüthner E, Malinowski M, Seehofer D, Pratschke J, Stockmann M.
Regeneration of Liver Function Capacity After Partial Liver Resection is Impaired in Case of Postoperative Bile Leakage.

World J Surg. 2016;40:2221-8.


von Loeffelholz C, Horn P, Birkenfeld AL, Claus RA, Metzing BU, Döcke S, Jahreis G, Heller R, Hoppe S, Stockmann M, Lock JF, Rieger A, Weickert MO, Settmacher U, Rauchfuß F, Pfeiffer AF, Bauer M, Sponholz C.
Fetuin A is a Predictor of Liver Fat in Preoperative Patients with Nonalcoholic Fatty Liver Disease.

J Invest Surg. 2016;16:1-9.


Jara M, Bednarsch J, Malinowski M, Pratschke J, Stockmann M.
Effects of oxaliplatin-based chemotherapy on liver function - An analysis of impact and functional recovery using the LiMAx test.

Langenbecks Arch Surg. 2016;401:33-41.


Malinowski M, Lock JF, Seehofer D, Gebauer B, Schulz A, Demirel L, Bednarsch J, Stary V, Neuhaus P, Stockmann M.
Preliminary study on liver function changes after trisectionectomy with versus without prior portal vein embolization.

Surg Today. 2016;46:1053-61.


Bednarsch J, Menk M, Malinowski M, Weber-Carstens S, Pratschke J, Stockmann M.
13C breath tests are feasible in patients with extra corporeal membrane oxygenation devices.

Artif Organs. 2016;40:692-8.


Jara M, Bednarsch J, Malinowski M, Pratschke J, Stockmann M.
Effects of oxaliplatin-based chemotherapy on liver function--an analysis of impact and functional recovery using the LiMAx test.

Langenbecks Arch Surg. 2016;401:33-41.


Feldheiser A, Pavlova V, Weimann K, Hunsicker O, Stockmann M, Koch M, Giebels A, Wernecke KD, Spies CD.
Haemodynamic Optimization by Oesophageal Doppler and Pulse Power Wave Analysis in Liver Surgery: A Randomised Controlled Trial.

PLoS One. 2015;10:e0132715.


Jara M, Reese T, Malinowski M, Valle E, Seehofer D, Puhl G, Neuhaus P, Pratschke J, Stockmann M.
Reductions in post-hepatectomy liver failure and related mortality after implementation of the LiMAx algorithm in preoperative work-up: a single-centre analysis of 1170 hepatectomies of one or more segments.

HPB (Oxford). 2015;17:651-8.


Pivovarova O, von Loeffelholz C, Ilkavets I, Sticht C, Zhuk S, Murahovschi V, Lukowski S, Döcke S, Kriebel J, de Las Heras Gala T, Malashicheva A, Kostareva A, Lock JF, Stockmann M, Grallert H, Gretz N, Dooley S, Pfeiffer AF, Rudovich N.
Modulation of Insulin Degrading Enzyme activity and liver cell proliferation.

Cell Cycle. 2015;14:2293-300.


Bednarsch J, Jara M, Lock JF, Malinowski M, Pratschke J, Stockmann M.
Noninvasive diagnosis of chemotherapy induced liver injury by LiMAx test - two case reports and a review of the literature.

BMC Res Notes. 2015;8:99


Malinowski M, Stary V, Lock JF, Schulz A, Jara M, Seehofer D, Gebauer B, Denecke T, Geisel D, Neuhaus P, Stockmann M.
Factors influencing hypertrophy of the left lateral liver lobe after portal vein embolization.

Langenbecks Arch Surg. 2015;400:237-46.


Jara M, Malinowski M, Bahra M, Stockmannn M, Schulz A, Pratschke J, Puhl G.
Bovine pericardium for portal vein reconstruction in abdominal surgery: a surgical guide and first experiences in a single center.

Dig Surg. 2015;32:135-41.


Gebhardt S, Jara M, Malinowski M, Seehofer D, Puhl G, Pratschke J, Stockmann M.
Risk Factors of Metabolic Disorders After Liver Transplantation: An Analysis of Data From Fasted Patients.

Transplantation. 2015;99:1243-9.


Malinowski M, Geisel D, Stary V, Denecke T, Seehofer D, Jara M, Baron A, Pratschke J, Gebauer B, Stockmann M.
Portal vein embolization with plug/coils improves hepatectomy outcome.

J Surg Res. 2015;194:202-11.


Geisel D, Lüdemann L, Fröling V, Malinowski M, Stockmann M, Baron A, Gebauer B, Seehofer D, Prasad V, Denecke T.
Imaging-based evaluation of liver function: comparison of  99mTc-mebrofenin hepatobiliary scintigraphy and Gd-EOB-DTPA-enhanced MRI.

Eur Radiol. 2015;25:1384-91.


Hoppe S, von Loeffelholz C, Lock JF, Doecke S, Sinn BV, Rieger A, Malinowski M, Pfeiffer AF, Neuhaus P, Stockmann M.
Nonalcoholic Steatohepatits and Liver Steatosis Modify Partial Hepatectomy Recovery.

J Invest Surg. 2015;28:24-31.


Murahovschi V, Pivovarova O, Ilkavets I, Dmitrieva RM, Döcke S, Keyhani-Nejad F, Gögebakan O, Osterhoff M, Kemper M, Hornemann S, Markova M, Klöting N, Stockmann M, Weickert MO, Lamounier-Zepter V, Neuhaus P, Konradi A, Dooley S, von Loeffelholz C, Blüher M, Pfeiffer AF, Rudovich N.
WISP1 is a novel adipokine linked to inflammation in obesity.

Diabetes. 2015;64:856-66.


Jara M, Malinowski M, Lüttgert K, Schott E, Neuhaus P, Stockmann M.
Prognostic value of enzymatic liver function for the estimation of short-term survival of liver transplant candidates: a prospective study with the LiMAx test.

Transpl Int. 2015;28:52-8.


Jara M, Bednarsch J, Valle E, Lock JF, Malinowski M, Schulz A, Seehofer D, Jung T, Stockmann M.
Reliable assessment of liver function using LiMAx.

J Surg Res. 2015;193:184-9.


Faber W, Sharafi S, Stockmann M, Dennecke T, Bahra M, Klein F, Malinowski MB, Schott E, Neuhaus P, Seehofer D.
Patient age and extent of liver resection influence outcome of liver resection for hepatocellular carcinoma in non-cirrhotic liver.

Hepatogastroenterology. 2014;61:1925-30.


Faber W, Stockmann M, Kruschke JE, Denecke T, Bahra M, Seehofer D.
Implication of microscopic and macroscopic vascular invasion for liver resection in patients with hepatocellular carcinoma.

Dig Surg. 2014;31:204-9.


Kiefer S, Schäfer M, Bransch M, Brimmers P, Bartolomé D, Baños J, Orr J, Jones D, Jara M, Stockmann M.
A novel personal health system with integrated decision support and guidance for the management of chronic liver disease.

Stud Health Technol Inform. 2014;205:83-7.


Jara M, Bednarsch J, Malinowski M, Lüttgert K, Orr J, Puhl G, Seehofer D, Neuhaus P, Stockmann M.
Predictors of quality of life in patients evaluated for liver transplantation.

Clin Transplant. 2014;28:1331-8.


Geisel D, Lüdemann L, Gebauer B, Fröling V, Prasad V, Heimann U, Stockmann M, Malinowski M, Hamm B, Brenner W, Denecke T.
Optimized separation of left and right liver lobe in dynamic 99mTc-mebrofenin hepatobiliary scintigraphy using a hybrid SPECT-CT scanner.

Ann Nucl Med. 2014;28:897-902.


Malinowski M, Jara M, Lüttgert K, Orr J, Lock JF, Schott E, Stockmann M.
Enzymatic Liver Function Capacity Correlates with Disease Severity of Patients with Liver Cirrhosis: A Study with the LiMAx Test.

Dig Dis Sci. 2014;59:2983-91.


Brinkhaus G, Lock JF, Malinowski M, Denecke T, Neuhaus P, Hamm B, Gebauer B, Stockmann M.
CT-Guided High-Dose-Rate Brachytherapy of Liver Tumours Does Not Impair Hepatic Function and Shows High Overall Safety and Favourable Survival Rates.

Ann Surg Oncol. 2014;21:4284-92.


Jara M, Schulz A, Malinowski M, Puhl G, Lock JF, Seehofer D, Neuhaus P, Stockmann M.
Growth hormone/insulin-like growth factor 1 dynamics in adult living donor liver transplantation.

Liver Transpl. 2014;20:1118-26.


Reiter R, Freise C, Jöhrens K, Kamphues C, Seehofer D, Stockmann M, Somasundaram R, Asbach P, Braun J, Samani A, Sack I.
Wideband MRE and static mechanical indentation of human liver specimen: sensitivity of viscoelastic constants to the alteration of tissue structure in hepatic fibrosis.

J Biomech. 2014;47:1665-74.


Jara M, Bednarsch J, Lock JF, Malinowski M, Schulz A, Seehofer D, Stockmann M.
Enhancing safety in liver surgery using a new diagnostic tool for evaluation of actual liver function capacity - The LiMAx test.

Dtsch Med Wochenschr. 2014;139:387-91.


Geisel D, Gebauer B, Malinowski M, Stockmann M, Denecke T.
Comparison of CT and MRI artefacts from coils and vascular plugs used for portal vein embolization.

Eur J Radiol. 2014;83:692-5.


Faber W, Stockmann M, Schirmer C, Möllerarnd A, Denecke T, Bahra M, Klein F, Schott E, Neuhaus P, Seehofer D.
Significant impact of patient age on outcome after liver resection for HCC in cirrhosis.

Eur J Surg Oncol. 2014;40:208-13.


Geisel D, Malinowski M, Powerski MJ, Wüstefeld J, Heller V, Denecke T, Stockmann M, Gebauer B.
Improved Hypertrophy of Future Remnant Liver after Portal Vein Embolization with Plugs, Coils and Particles.

Cardiovasc Intervent Radiol. 2014;37:1251-8.


Kaffarnik MF, Lock JF, Vetter H, Ahmadi N, Lojewski C, Malinowski M, Neuhaus P, Stockmann M.
Early diagnosis of sepsis-related hepatic dysfunction and its prognostic impact on survival: a prospective study with the LiMAx test.

Crit Care. 2013;17:R259.


Steinbach C, Stockmann M, Jara M, Bednarsch J, Lock JF.
Accidentally Ingested Toothpicks Causing Severe Gastrointestinal Injury: A Practical Guideline for Diagnosis and Therapy Based on 136 Case Reports.

World J Surg. 2014;38:371-7.


Holzhütter HG, Lock JF, Taheri P, Bulik S, Goede A, Stockmann M.
Assessment of hepatic detoxification activity: proposal of an improved variant of the (13)c-methacetin breath test.

PLoS One. 2013;


Döcke S, Lock JF, Birkenfeld AL, Hoppe S, Lieske S, Rieger A, Raschzok N, Sauer IM, Florian S, Osterhoff MA, Heller R, Herrmann K, Lindenmüller S, Horn P, Bauer M, Weickert MO, Neuhaus P, Stockmann M, Möhlig M, Pfeiffer AF, von Loeffelholz C.
Elevated hepatic chemerin gene expression in progressed human non-alcoholic fatty liver disease.

Eur J Endocrinol. 2013;169:547-57.


Geisel D, Lüdemann L, Wagner C, Stelter L, Grieser C, Malinowski M, Stockmann M, Seehofer D, Hamm B, Gebauer B, Denecke T.
Evaluation of gadolinium-EOB-DTPA uptake after portal vein embolization: value of an increased flip angle.

Acta Radiol.


Strücker B, Stockmann M, Denecke T, Neuhaus P, Seehofer D.

Intraoperative Placement of External Biliary Drains for Prevention and Treatment of Bile Leaks After Extended Liver Resection Without Bilioenteric Anastomosis.

World J Surg. 2013;37:2629-34.


Lock JF, Kotobi AN, Malinowski M, Schulz A, Jara M, Neuhaus P, Stockmann M.
Predicting the prognosis in acute liver failure: results from a retrospective pilot study using the LiMAx test.

Ann Hepatol. 2013;12:556-62.


Geisel D, Lüdemann L, Keuchel T, Malinowski M, Seehofer D, Stockmann M, Hamm B, Gebauer B, Denecke T.
Increase in left liver lobe function after preoperative right portal vein embolisation assessed with gadolinium-EOB-DTPA MRI.

Eur Radiol. 2013;23:2555-60.

Stockmann M, Lock JF
How Far Is the Development of  13C-Liver-Function Breath Tests?

Dig Dis Sci. 2013;58:1804-5.

Lederer A, lt Seehofer D, Schirmeier A, Levasseur S, Stockmann M, Nüssler AK, Menger MD, Neuhaus P, Rayes N.
Postoperative bile leakage inhibits liver regeneration after 70% hepatectomy in rats.

J Invest Surg. 2013;26:36-45.

Faber W, lt Sharafi S, Stockmann M, Denecke T, Sinn B, Puhl G, Bahra M, Malinowski MB, Neuhaus P, Seehofer D.
Long-term results of liver resection for hepatocellular carcinoma in noncirrhotic liver.

Surgery. 2013;153:510-7.


Eisele RM, lt Chopra SS, Lock JF, Glanemann M.
Treatment of recurrent hepatocellular carcinoma confined to the liver with repeated resection and radiofrequency ablation: a single center experience.

Technol Health Care. 2013;21:9-18.


Kaffarnik MF, Lock JF, Wassilew G, Neuhaus P.
The use of bedside electromagnetically guided nasointestinal tube for jejunal feeding of critical ill surgical patients.

Technol Health Care. 2013;21:1-8.


Rayes N, Pilarski T, Stockmann M, Bengmark S, Neuhaus P, Seehofer D.
Effect of pre- and probiotics on liver regeneration after resection: a randomised, double-blind pilot study.

Benef Microbes. 2012;3:237-44.

J.F.Lock, A.N. Kotobi, M. Malinowski, M. Jara, A. Schulz, P. Neuhaus und M. Stockmann
Nichtinvasive Diagnsotik der Leberfunktion in der Transplantationsmedizin

Verdauungskrankheiten, Jahrgang 30 in press

Lock JF, Malinowski M, Seehofer D, Hoppe S, Röhl RI, Niehues SM, Neuhaus P, Stockmann M.
Function and volume recovery after partial hepatectomy: influence of preoperative liver function, residual liver volume, and obesity

Langenbecks Arch Surg.
2012 Jun 24

Seehofer D, Nebrig M, Denecke T, Kroencke T, Weichert W, Stockmann M, Somasundaram R, Schott E, Puhl G, Neuhaus P.
Impact of neoadjuvant transarterial chemoembolization on tumor recurrence and patient survival after liver transplantation for hepatocellular carcinoma: a retrospective analysis

Clin Transplant. 2012;26:764-74.


Faber W, Seehofer D, Neuhaus P, Stockmann M, Denecke T, Kalmuk S, Warnick P, Bahra M
Repeated liver resection for recurrent hepatocellular carcinoma

J Gastroenterol Hepatol.

Stockmann M
Resection of hepatocellular carcinoma in patients without cirrhosis

Br J Surg.

J. F. Lock, M. Malinowski, E. Schwabauer, P. Martus, J. Pratschke, D. Seehofer, G. Puhl, P. Neuhaus and M. Stockmann
Initial liver graft function is a reliable predictor of tacrolimus trough levels during the first post-transplant week

Clin Transplant.

Kaffarnik MF, Lock JF, Seehofer D, Stockmann M, Neuhaus P
Liver Resections - Perioperative Care


Kulozik P, Jones A, Mattijssen F, Rose AJ, Reimann A, Strzoda D, Kleinsorg S, Raupp C, Kleinschmidt J, Müller-Decker K, Wahli W, Sticht C, Gretz N, von Loeffelholz C, Stockmann M, Pfeiffer A, Stöhr S, Dallinga-Thie GM, Nawroth PP, Berriel Diaz M, Herzig S
Hepatic Deficiency in Transcriptional Cofactor TBL1 Promotes Liver Steatosis and Hypertriglyceridemia

Cell Metab.
2011 Apr 6;13(4):389-400

Malinowski M, Stockmann M
LiMAx-Test: Ein neues Verfahren zur Bestimmung der Leberfunktionsreserve


Malinowski M, Martus P, Lock JF, Neuhaus P, Stockmann M
Systemic influence of immunosuppressive drugs on small and large bowel transport and barrier function

Transpl Int.
2011 Feb;24(2):184-93.


Chopra SS, Eisele RM, Denecke T, Stockmann M, Lange T, Eulenstein S, Schmidt SC, Neuhaus P
Advances in image guided conventional and minimal invasive liver surgery

Minerva Chir.
2010 Aug;65(4):463-78.

Niehues SM, Unger JK, Malinowski M, Neymeyer J, Hamm B, Stockmann M.
Liver volume measurement: reason of the difference between in vivo CT-volumetry and intraoperative ex vivo determination and how to cope it

Eur J Med Res.
2010 Aug 20;15(8):345-50

J. Lock, T. Reinhold, A. Bloch, M. Malinowski, S. C. Schmidt, P. Neuhaus and M. Stockmann
The cost of graft failure and other severe complications after liver transplantation - experience from a German Transplant Center

Ann Tansplant.
2010; 15(3): 11-8.

M. Malinowski, J. Pratschke, J.F. Lock, P. Neuhaus, M. Stockmann
Effect of Tacrolimus Dosing on Glucose Metabolism in an Experimental Rat Model

Ann Tansplant.
2010; 15(3): 60-5

M. Stockmann, J. F. Lock, M. Malinowski, S. M. Niehues, D. Seehofer and P. Neuhaus
The LiMAx test: a new liver function test for predicting postoperative outcome in liver surgery

HPB (Oxford)
2010 Mar;12(2):139-146.

M. Stockmann, J. F. Lock, M. Malinowski and P. Neuhaus
Evaluation of early liver graft performance by the indocyanine green plasma disappearance rate

Liver Transpl.
2010 Jun;16(6):793-4;
author reply 795-6

M. Stockmann, J. F. Lock, M. Malinowski, D. Seehofer, G. Puhl, J. Pratschke and P. Neuhaus
How to define initial poor graft function after liver transplantation? - a new functional definition by the LiMAx test

Transpl Int.
2010 Oct;23(10):1023-32

J. F. Lock, E. Schwabauer, P. Martus, N. Videv, J. Pratschke, M. Malinowski, P. Neuhaus and M. Stockmann
Early diagnosis of primary nonfunction and indication for reoperation after liver transplantation

Liver Transpl.
2010;16(2): 172-80


M. Malinowski, J. Pratschke, A. Jurisch, P. Neuhaus and M. Stockmann
Impairment of insulin production is induced by a toxic tacrolimus dosage

Chirurgisches Forum

Stockmann M, Lock JF
Wie gut funktioniert meine Leber? Diagnostik der Leberfunktion mit dem LiMAx-Test

Das Lebermagazin

J. F. Lock, P. Taheri, S. Bauer, H.-G. Holzhütter, M. Malinowski, P. Neuhaus and M. Stockmann
Interpretation of Non-Invasive Breath Tests Using 13C-Labelled Substrates - A Preeliminary Report with 13C-Methacetin

European Journal of Medical Research

M. Stockmann, J. F. Lock, B. Riecke, K. Heyne, P. Martus, M. Fricke, S. Lehmann, S. M. Niehues, M. Schwabe, A. J. Lemke and P. Neuhaus
Prediction of Postoperative Outcome After Hepatectomy With a New Bedside Test for Maximal Liver Function Capacity

Ann Surg

J. F. Lock, T. Reinhold, M. Malinowski, J. Pratschke, P. Neuhaus and M. Stockmann
The costs of postoperative liver failure and the economic impact of liver function capacity after extended liver resection-a single-center experience

Langenbecks Arch Surg
2009; 394(6):1047-56

M. Stockmann, M. Malinowski, J. F. Lock, D. Seehofer and P. Neuhaus
Factors influencing the indocyanine green (ICG) test: additional impact of acute cholestasis

Hepatogastroenterology 2009;56(91-92):734-8

M. Malinowski, P. Martus, P. Neuhaus and M. Stockmann
The influence of commonly used immunosuppressive drugs on the small bowel functions - a comparative experimental study

Ann Transplant


V. Schmitz, S. Laudi, F. Moeckel, G. Puhl, M. Stockmann, Z. V. Tran, A. Kahl, U. Neumann and P. Neuhaus
Chronic renal dysfunction following liver transplantation

Clin Transplant


D. Seehofer, M. Stockmann, A. Schirmeier, A. K. Nussler, S. Y. Cho, N. Rayes, M. Koch, R. Schiller, M. D. Menger and P. Neuhaus
Intraabdominal bacterial infections significantly alter regeneration and function of the liver in a rat model of major hepatectomy

Langenbecks Arch Surg


M. Stockmann, T. Konrad, S. Nolting, D. Hunerbein, K. D. Wernecke, H. Dobling, T. Steinmuller and P. Neuhaus
Major influence of liver function itself but not of immunosuppression determines glucose tolerance after living-donor liver transplantation

Liver Transpl


M. Stockmann, S. Nolting, T. Konrad, D. Hunerbein, H. Dobling, T. Steinmuller and P. Neuhaus
No influence of immunosuppression on insulin sensitivity and beta-cell function in living donor liver transplantation

Transplant Proc
2005; 37:1861-4

B. Riecke, P. Neuhaus and M. Stockmann
Major influence of oxygen supply on 13CO2:12CO2 ratio measurement by nondispersive isotope-selective infrared spectroscopy

2005;(6)10: 620-2


A. J. Kroesen, M. Stockmann, C. Ransco, J. D. Schulzke, M. Fromm and H. J. Buhr
Impairment of epithelial transport but not of barrier function in idiopathic pouchitis after ulcerative colitis

2002;(6)50: 821-6

M. Stockmann, B. E. Engelmann, J. M. Langrehr and P. Neuhaus
Influence of immunosuppressive drugs on intestinal epithelial transport function

Transplant Proc

M. Stockmann, T. Steinmuller, S. Nolting and P. Neuhaus
Posttransplant diabetes mellitus after orthotopic liver transplantation

Transplant Proc


T. Steinmuller, M. Stockmann, W. O. Bechstein, U. Settmacher, S. Jonas and P. Neuhaus
Liver transplantation and diabetes mellitus

Exp Clin Endocrinol Diabetes 2000;(6)108:401-5

M. Stockmann, H. Schmitz, M. Fromm, W. Schmidt, G. Pauli, P. Scholz, E. O. Riecken and J. D. Schulzke
Mechanisms of epithelial barrier impairment in HIV infection

Ann N Y Acad Sci


M. Stockmann, A. H. Gitter, D. Sorgenfrei, M. Fromm and J. D. Schulzke
Low edge damage container insert that adjusts intestinal forceps biopsies into Ussing chamber systems

Pflugers Arch


M. Stockmann, H. Schmitz, M. Fromm, W. Schmidt, K. Rokos, G. Pauli, P. Scholz, E. O. Riecken and J. D. Schulzke
The mechanism of diarrhea in HIV is based on an impaired epithelial barrier function that could be induced by a specific cytokine pattern

Ann N Y Acad Sci

M. Stockmann, M. Fromm, H. Schmitz, W. Schmidt, E. O. Riecken and J. D. Schulzke
Duodenal biopsies of HIV-infected patients with diarrhoea exhibit epithelial barrier defects but no active secretion


M. Stockmann, M. Fromm, E. Riecken and J. Schulzke
Nonmalabsorptive mechanisms of diarrhea in HIV infection

1998; (3-4)66:165-9

Back to content | Back to main menu